Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.
Sven K.
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Tripeptide (Lys-Pro-Val), fragment of α-MSH, studied around inflammation.
4.7 · 27 reviews
Buy KPV, research-grade — ≥99% HPLC, same-day shipping from the Netherlands. Tripeptide (Lys-Pro-Val) from α-MSH, studied around inflammation in gut and skin.
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Bacteriostatic water
Insulin needles
Alcohol swabs
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1 more for −10% off
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In research, KPV is all about one thing: calming inflammation. It is a small tripeptide — lysine, proline and valine — that forms the tail end of the body's own hormone α-MSH, which has long been known for its anti-inflammatory side. KPV is thought to carry that side with it: it calms inflammatory signals and is therefore looked at mainly around the gut and the skin, where inflammation plays a big role. At GradePurity you buy it purely as a research raw material, not for use in humans.
What is special about KPV is where it acts. Where many compounds work only on the outside of the cell, KPV is thought to enter the cell itself and slow the inflammatory machinery there — chiefly the NF-κB pathway, a central switch that drives the production of pro-inflammatory messengers (cytokines). Because it is small and stable, it is also taken up easily by cells. Most of what we know comes from lab and animal models. GradePurity supplies KPV for research only.
KPV isn't a standalone find but a fragment of something larger: it is the C-terminal piece of α-MSH (alpha-melanocyte-stimulating hormone), hence the synonym name α-MSH(11-13). It is precisely that tail piece that carries the anti-inflammatory action in research, without the pigment and appetite effects you see with full α-MSH or with related peptides. In the literature KPV is therefore often described as "the anti-inflammatory part" of α-MSH. We supply it as a research-grade vial.
Two research areas keep coming up with KPV: the gut and the skin. In gut models the focus is on inflammatory diseases such as Crohn's disease and ulcerative colitis, where KPV is taken up through the gut wall. In skin models it is about inflammation-related conditions and wound healing. In both cases the idea is the same: bring local inflammation down. This is explicitly pre-clinical and early research; GradePurity supplies KPV for the lab only, not as a treatment.
We deliberately leave the amount open: KPV is a research compound, and we don't provide human dosing advice. In the literature it is usually studied in small amounts per protocol, after reconstitution with bacteriostatic water. Need to convert amounts for a research setup? We have a dedicated calculator for that. Keep the reconstituted peptide refrigerated and use it within the recommended window.
KPV is known in research for a favourable profile — in keeping with its small size and its origin as a fragment of a natural hormone. In the studies that have been done, mostly mild reactions were reported. The honest caveat remains: large long-term data in humans is lacking, and effects depend heavily on the study design. GradePurity supplies KPV for research only.
In the Netherlands you may buy and sell KPV for experimental laboratory research that isn't applied to humans or animals. It's not a medicine: no KPV product is approved for human use anywhere, and it isn't prescribed. We therefore supply it strictly as a research-grade compound, not as a medicine or supplement.
With a peptide, reliable research hinges on one thing: knowing the vial contains what the label says. That's why we test every batch of KPV by HPLC for ≥99% purity and for identity, with a COA per lot, and ship it freeze-dried so it reaches you stable. That way you know exactly what you're holding — the exact specifications are in the table at the bottom of this page.
Verified buyers across the Netherlands
Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.
Sven K.
Verified purchase
Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.
Lotte v.d. B.
Verified purchase
Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.
Paul M.
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Next business day in Rotterdam. Well and discreetly packed, will definitely order again.
Marco R.
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Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.
Niels J.
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Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.
Jonas W.
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Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.
Eva R.
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Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.
Bram H.
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Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.
Femke S.
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Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.
Thijs M.
Verified purchase
Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.
Sven K.
Verified purchase
Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.
Lotte v.d. B.
Verified purchase
Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.
Paul M.
Verified purchase
Next business day in Rotterdam. Well and discreetly packed, will definitely order again.
Marco R.
Verified purchase
Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.
Niels J.
Verified purchase
Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.
Jonas W.
Verified purchase
Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.
Eva R.
Verified purchase
Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.
Bram H.
Verified purchase
Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.
Femke S.
Verified purchase
Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.
Thijs M.
Verified purchase
The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.
Tom B.
Verified purchase
The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.
Charlotte F.
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Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.
Anouk d. V.
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Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.
Lukas K.
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Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.
Sara P.
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Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.
Daniel S.
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Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.
Iris K.
Verified purchase
Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.
Joris V.
Verified purchase
Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.
Sanne D.
Verified purchase
Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.
Ruben T.
Verified purchase
The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.
Tom B.
Verified purchase
The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.
Charlotte F.
Verified purchase
Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.
Anouk d. V.
Verified purchase
Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.
Lukas K.
Verified purchase
Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.
Sara P.
Verified purchase
Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.
Daniel S.
Verified purchase
Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.
Iris K.
Verified purchase
Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.
Joris V.
Verified purchase
Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.
Sanne D.
Verified purchase
Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.
Ruben T.
Verified purchase