Research onlyFor laboratory research · Not intended for human or animal application
GradePurity

Melanotan II

Melanocortin research peptide, pigment and MSH.

4.4 · 41 reviews
99.2% HPLCLab-verifiedCosmetic researchResearch only
Melanotan II, research-grade peptide vial
€ 39,95

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Bacteriostatic water

Needed to reconstitute lyophilised vials.

Insulin needles

Alcohol swabs

Quantity

1
Bulk discountup to −26%

1 more for −10% off

Free shipping from €125

In stock
Ships from NL · 1–2 day EU delivery
30-day returns
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Melanotan 2 (MT-II) is a synthetic research peptide and an analogue of α-MSH, the hormone that drives pigment production in the body. In research it is studied around the melanocortin pathway: pigmentation of the skin, and alongside that appetite and libido. It was originally developed at the University of Arizona as a possible way to protect the skin through pigment. At GradePurity you buy melanotan 2 as a research-grade peptide: ≥99% HPLC purity and same-day shipping from the Netherlands.

What does melanotan 2 do?

Melanotan 2 is best known in research around pigment. It is thought to stimulate the melanocytes, the cells that produce pigment, through the same pathway as the natural hormone α-MSH. Research also looks at effects on appetite and libido, because the peptide acts on several melanocortin receptors.

How does melanotan 2 work?

Melanotan 2 is a synthetic analogue of α-MSH (alpha-melanocyte-stimulating hormone). It acts as a non-selective agonist at the melanocortin receptors MC1, MC3, MC4 and MC5. Through MC1 it is linked to pigment formation in the skin; through MC4 to appetite and sexual function. Because it acts on several receptors at once, its effect profile is broader than that of the natural hormone. Most of the research comes from animal models and early studies.

Melanotan 2 vs melanotan 1, the difference

Melanotan 1 and melanotan 2 are often confused, but they are different substances. Melanotan 1 (afamelanotide) is now an approved medicine used under medical supervision for a rare light-sensitivity condition. Melanotan 2 has never been approved for that and remains a research substance: it acts on more receptors, stays active longer and therefore has a broader effect and side-effect profile. GradePurity supplies melanotan 2 as a research peptide only; we do not carry melanotan 1.

Melanotan 2 dosage and reconstitution

Melanotan 2 ships as a lyophilised vial that you mix yourself with bacteriostatic water. The literature usually works with a build-up phase at low amounts followed by a maintenance phase; the exact protocols vary by study. GradePurity gives no dosing or administration advice itself: we supply melanotan 2 as a research peptide only, and the details on this page (purity, vial size) are intended for your research documentation. After mixing, store the vial in the fridge (2–8 °C), protected from light.

Side effects and safety of melanotan 2

Melanotan 2 is a research substance that has never been approved as a medicine, and its safety in humans is not established. The literature and reports mention, among other things, nausea, flushing, and the darkening of existing moles. There are concerns about a possibly increased risk of skin cancer, although this has not been confirmed in long-term studies.

Is melanotan 2 legal?

Melanotan 2 is not approved as a medicine in the Netherlands or the rest of the EU, and it may not be sold or used for human application. As a research-grade peptide, however, it may be bought and held for laboratory research; consumption or cosmetic use is explicitly outside that. GradePurity therefore supplies melanotan 2 for research only, not for human use.

Purity and lab testing

Every batch of melanotan 2 is checked in the lab for purity (≥99%) and identity. So you know exactly what you are holding, that is the main difference from anonymous suppliers. The exact specifications are in the table at the bottom of this page.

Frequently asked questions

What our customers say.

Verified buyers across the Netherlands

★★★★★4.9 / 5Verified
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

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