Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.
Sven K.
Verified purchase
SNAP-8
Cosmetic octapeptide, anti-wrinkle research.
4.4 · 16 reviews≥ 99.1% HPLCLab-verifiedCosmetic researchResearch only
Buy SNAP-8 peptide, Acetyl Octapeptide-3, ≥99% HPLC, same-day from the Netherlands. Synthetic octapeptide, studied in cosmetic research around expression lines. Research only.
€ 24,95
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Ships from NL · 1–2 day EU delivery
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SNAP-8 (Acetyl Octapeptide-3) is a synthetic octapeptide of eight amino acids studied in cosmetic research around expression lines. It is the extended successor to the well-known Argireline (Acetyl Hexapeptide-3): where Argireline has six amino acids, SNAP-8 has eight. In research it is linked to the SNARE protein complex, which governs signal transfer between nerve and muscle, the pathway described in the literature as a "botox-like", non-invasive action. At GradePurity you buy SNAP-8 as a research-grade peptide: ≥99% HPLC purity and same-day shipping from the Netherlands.
What does SNAP-8 do?
SNAP-8 is best known in cosmetic research around expression lines, the wrinkles caused by repeated muscle movement, such as frown lines and creases around the eyes. It is thought to act on the signal transfer that makes the small facial muscles contract, via the so-called SNARE complex. Because of this it is described in the literature as a topical, non-invasive route that moves in the direction of what injections aim for, but without a needle.
How does SNAP-8 work?
SNAP-8 (Acetyl Octapeptide-3) is derived from the N-terminal end of SNAP-25, a protein that plays a key role in the SNARE complex. That complex is needed to release vesicles containing the messenger acetylcholine at the nerve-to-muscle junction. It is thought that SNAP-8 competes with this complex and so inhibits the release of acetylcholine, which would make muscle contraction weaker. It is precisely this mechanism that is studied in cosmetic research; most of the work comes from in-vitro and formulation studies.
SNAP-8 vs. Argireline, the difference
SNAP-8 and Argireline are often mentioned together, because they act on the same route. The difference is in the length: Argireline (Acetyl Hexapeptide-8, formerly Acetyl Hexapeptide-3) has six amino acids, SNAP-8 has eight. SNAP-8 was developed as an extended variant, and supplier literature claims a stronger interaction with the SNARE complex. Independent comparative studies between the two are limited, however, so the claim "stronger than Argireline" rests mainly on manufacturer data. GradePurity sells SNAP-8 as a single research peptide; we do not carry Argireline, the comparison is here purely for context.
The "botox-like" comparison
SNAP-8 is often called "botox in a bottle" online. That nickname refers to the idea that the peptide, like botulinum toxin, affects signal transfer to muscles, but the resemblance is limited and the action is very different. Botox is a medicine that is injected and blocks the nerve for a long time; SNAP-8 is a cosmetically studied peptide applied topically that would have at most a mild, temporary effect on the signal route. The two are not interchangeable.
SNAP-8 as a serum and in cosmetic formulations
On the market you mostly encounter SNAP-8 processed into finished serums and creams, usually at a low concentration and combined with other ingredients. In research it is also combined with related peptides such as GHK-Cu or Leuphasyl to study several routes at once. Important: at GradePurity you do not buy a finished serum, but the lyophilised research-grade vial that you mix yourself for laboratory research. The specifications you need for your formulation or documentation, purity, vial size, sequence, are in the table at the bottom of this page.
SNAP-8 reconstitution and storage
SNAP-8 is supplied as a lyophilised powder in a vial. For research it is mixed with distilled water or a cosmetic-grade buffer; GradePurity gives no dosing or administration advice, because we supply it solely as a research peptide. Store the unopened vial dry, dark and cool. After mixing, the solution goes in the fridge (2–8 °C), protected from light; for longer storage the vial can go in the freezer (−20 °C). The details on this page are intended for research documentation.
Purity and lab testing
Every batch of SNAP-8 is checked in the lab for purity (≥99% HPLC) and identity. So you know exactly what you are holding, that is the main difference from anonymous suppliers. A certificate of analysis (COA) is available per lot. The exact specifications are in the table at the bottom of this page.
Frequently asked questions
What our customers say.
Verified buyers across the Netherlands
★★★★★4.9 / 5Verified
BPC-157
Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.
Lotte v.d. B.
Verified purchase
Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.
Paul M.
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Next business day in Rotterdam. Well and discreetly packed, will definitely order again.
Marco R.
Verified purchase
Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.
Niels J.
Verified purchase
Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.
Jonas W.
Verified purchase
Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.
Eva R.
Verified purchase
Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.
Bram H.
Verified purchase
Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.
Femke S.
Verified purchase
Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.
Thijs M.
Verified purchase
Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.
Sven K.
Verified purchase
Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.
Lotte v.d. B.
Verified purchase
Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.
Paul M.
Verified purchase
Next business day in Rotterdam. Well and discreetly packed, will definitely order again.
Marco R.
Verified purchase
Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.
Niels J.
Verified purchase
Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.
Jonas W.
Verified purchase
Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.
Eva R.
Verified purchase
Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.
Bram H.
Verified purchase
Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.
Femke S.
Verified purchase
Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.
Thijs M.
Verified purchase
The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.
Tom B.
Verified purchase
The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.
Charlotte F.
Verified purchase
Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.
Anouk d. V.
Verified purchase
Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.
Lukas K.
Verified purchase
Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.
Sara P.
Verified purchase
Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.
Daniel S.
Verified purchase
Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.
Iris K.
Verified purchase
Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.
Joris V.
Verified purchase
Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.
Sanne D.
Verified purchase
Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.
Ruben T.
Verified purchase
The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.
Tom B.
Verified purchase
The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.
Charlotte F.
Verified purchase
Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.
Anouk d. V.
Verified purchase
Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.
Lukas K.
Verified purchase
Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.
Sara P.
Verified purchase
Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.
Daniel S.
Verified purchase
Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.
Iris K.
Verified purchase
Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.
Joris V.
Verified purchase
Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.
Sanne D.
Verified purchase
Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.
Ruben T.
Verified purchase
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