Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.
Sven K.
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Gonadorelin
Gonadotropin-releasing hormone, 10 amino acids.
4.4 · 19 reviews≥ 99.2% HPLCLab-verifiedResearch only
Buy gonadorelin, GnRH decapeptide (research grade), ≥99% HPLC, same-day from the Netherlands. Studied around the LH/FSH axis. Research only.
€ 24,95
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Bacteriostatic water
Needed to reconstitute lyophilised vials.
Insulin needles
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Bulk discountup to −26%
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Ships from NL · 1–2 day EU delivery
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Gonadorelin is a synthetic peptide identical to the body-own gonadotropin-releasing hormone (GnRH, also known as LHRH). It is a decapeptide of ten amino acids studied in research around the hypothalamic-pituitary-gonadal axis: it signals the pituitary to release the hormones LH and FSH. As a medicine it was used in fertility and diagnostic research (brand names Factrel and LutrePulse), but those are largely off the market. At GradePurity you buy gonadorelin as a research-grade peptide: a lyophilised vial with ≥99% HPLC purity, shipped same-day from the Netherlands.
What does gonadorelin do?
Gonadorelin is the synthetic form of GnRH (gonadotropin-releasing hormone), the hormone with which the hypothalamus drives the pituitary. In short: gonadorelin signals the pituitary to release two other hormones, LH (luteinizing hormone) and FSH (follicle-stimulating hormone). Those two in turn drive the gonads. In research, gonadorelin is therefore used to study the pituitary-gonadal axis. It was also used as a medicine in fertility research and diagnostics, but those branded products (Factrel, LutrePulse) are largely off the market.
How does gonadorelin work?
What is special about gonadorelin lies in the rhythm. The pituitary responds to pulses of GnRH, not to a constant stream. When gonadorelin is given in short pulses in research, it stimulates the release of LH and FSH, it mimics the natural rhythm of the hypothalamus. When it is given continuously, the opposite happens: the receptors become insensitive and LH/FSH release falls. That dual behaviour, stimulating in pulses, suppressing when continuous, is exactly why gonadorelin is of interest in research. What we know about this comes from the clinical and scientific literature.
Gonadorelin vs. hCG
Gonadorelin and hCG are often compared because both relate to the sex-hormone axis, but they act at a very different point. Gonadorelin works at the top of the chain: it prompts the pituitary to make LH and FSH itself. hCG skips that step, it mimics LH and acts directly on the gonads, bypassing the pituitary. In the research and TRT context, gonadorelin is therefore seen as the substance that keeps the natural axis switched on, while hCG mimics the axis from below. GradePurity does not sell hCG; this comparison is here purely for information.
Gonadorelin and the testicular axis (TRT research)
In the context of testosterone replacement (TRT), gonadorelin is a much-discussed topic. The idea behind it: during an external testosterone course, the body-own LH/FSH production stalls, which makes the gonads less active. It is thought that pulsatile GnRH stimulation may keep that axis switched on in research. What is known about this is described in the scientific literature.
Side effects of gonadorelin
In the clinical literature, gonadorelin is generally well tolerated. The described side effects are mostly mild: headache, nausea and an irritated or painful injection site; sometimes hot flushes. These are observations from medical use under supervision, not data that says anything about laboratory use. GradePurity supplies gonadorelin solely as a research substance and gives no dosing or safety advice for personal use. For the full side effects we refer to the medical literature and a doctor or pharmacist.
Reconstituting and storing gonadorelin
Gonadorelin is supplied as a lyophilised powder in a vial. For research it is mixed with bacteriostatic water; GradePurity gives no dosing or administration advice. Store the unopened vial dry, dark and cool. Gonadorelin in solution is less stable than many other peptides: after mixing it goes in the fridge (2–8 °C), protected from light, and is used within a short time; for longer storage the unopened vial can go in the freezer. The specifications in the table at the bottom of this page are intended for your research documentation.
Purity and lab testing
Every batch of gonadorelin is checked in the lab for purity (≥99% HPLC) and identity. Precisely for a substance whose branded medicine is off the market, that testing is what sets it apart from anonymous suppliers: you know exactly what you are holding. Per lot we record the purity and identity data. The exact specifications, sequence, molecular weight and purity, are in the table at the bottom of this page.
Frequently asked questions
What our customers say.
Verified buyers across the Netherlands
★★★★★4.9 / 5Verified
BPC-157
Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.
Lotte v.d. B.
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Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.
Paul M.
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Next business day in Rotterdam. Well and discreetly packed, will definitely order again.
Marco R.
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Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.
Niels J.
Verified purchase
Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.
Jonas W.
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Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.
Eva R.
Verified purchase
Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.
Bram H.
Verified purchase
Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.
Femke S.
Verified purchase
Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.
Thijs M.
Verified purchase
Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.
Sven K.
Verified purchase
Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.
Lotte v.d. B.
Verified purchase
Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.
Paul M.
Verified purchase
Next business day in Rotterdam. Well and discreetly packed, will definitely order again.
Marco R.
Verified purchase
Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.
Niels J.
Verified purchase
Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.
Jonas W.
Verified purchase
Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.
Eva R.
Verified purchase
Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.
Bram H.
Verified purchase
Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.
Femke S.
Verified purchase
Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.
Thijs M.
Verified purchase
The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.
Tom B.
Verified purchase
The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.
Charlotte F.
Verified purchase
Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.
Anouk d. V.
Verified purchase
Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.
Lukas K.
Verified purchase
Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.
Sara P.
Verified purchase
Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.
Daniel S.
Verified purchase
Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.
Iris K.
Verified purchase
Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.
Joris V.
Verified purchase
Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.
Sanne D.
Verified purchase
Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.
Ruben T.
Verified purchase
The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.
Tom B.
Verified purchase
The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.
Charlotte F.
Verified purchase
Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.
Anouk d. V.
Verified purchase
Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.
Lukas K.
Verified purchase
Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.
Sara P.
Verified purchase
Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.
Daniel S.
Verified purchase
Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.
Iris K.
Verified purchase
Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.
Joris V.
Verified purchase
Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.
Sanne D.
Verified purchase
Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.
Ruben T.
Verified purchase
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