Research onlyFor laboratory research · Not intended for human or animal application
GradePurity

IGF-1 LR3

Long R3 IGF-1, long-acting growth factor variant.

4.6 · 38 reviews
98.5% HPLCLab-verifiedPremiumResearch only
IGF-1 LR3, research-grade peptide vial
€ 89,95

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Bacteriostatic water

Needed to reconstitute lyophilised vials.

Insulin needles

Alcohol swabs

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1
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Ships from NL · 1–2 day EU delivery
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IGF-1 LR3 (Long R3 IGF-1) is a synthetic, longer-acting variant of IGF-1, the growth factor your body makes itself under the influence of growth hormone. A small change to the molecule lets it evade the proteins that normally clear IGF-1 quickly, so it stays active far longer (around 20-30 hours in research) and acts more strongly. That's why it's popular in research around muscle and cell growth. At GradePurity you buy IGF-1 LR3 as a research-grade vial: ≥98% HPLC purity and same-day shipping from the Netherlands.

What does IGF-1 LR3 do?

IGF-1 LR3 is known in research mainly for growth: it's the long-acting version of IGF-1, the growth factor that does the actual work in the body after growth hormone has sent its signal. In studies it's linked to the building and repair of muscle tissue and to cell growth in general, which is exactly why it gets so much attention in the bodybuilding corner. Because the LR3 variant stays active far longer than ordinary IGF-1, it's more attractive to work with in research. At GradePurity you buy it purely as a research peptide, not for use in humans.

How does IGF-1 LR3 work?

IGF-1 LR3 acts on the same receptor as the body's own IGF-1 and switches on the signals involved in growth and repair there. The difference is in how long it lasts: normally IGF-1 is quickly cleared by binding proteins in the blood, but the change in LR3 lets it escape that. So in research it stays active far longer, around 20 to 30 hours, and acts more strongly than the natural form. Most of the work on this comes from cell and animal studies.

IGF-1 LR3 vs ordinary IGF-1

The difference between IGF-1 LR3 and "ordinary" IGF-1 isn't in what it does, but in how long and how strongly. Natural IGF-1 is quickly cleared in the body and only briefly active; the LR3 variant is modified to evade that clearance, making it several times more potent and far longer-lasting. For research that's convenient, because one administration lasts longer. Important: the natural IGF-1 that doctors measure in blood is a different story from this research variant, we supply only the LR3 research compound.

IGF-1 LR3 and the growth hormone axis

IGF-1 doesn't stand alone: it's the substance through which growth hormone does much of its work. Give the body more growth-hormone signal, for example in research with a GHRH analogue like CJC-1295 or a secretagogue like ipamorelin, and the liver makes more IGF-1. IGF-1 LR3 puts that final step in place directly, without the detour via growth hormone. If you want the upstream side of that axis, you'll find CJC-1295 and ipamorelin on their own in our range.

IGF-1 LR3 dosage

We deliberately leave the amount open: IGF-1 LR3 is a research compound, and we don't provide human dosing advice. It's a potent protein used in research in very small, microgram amounts, usually after reconstitution with bacteriostatic water or a mild acetic acid solution. Need to convert amounts for a research setup? We have a dedicated calculator for that. Note the storage instructions: don't refreeze it once dissolved.

IGF-1 LR3 side effects

Because IGF-1 LR3 acts on blood sugar and cell growth, its risk profile is more serious than that of many other peptides. The literature mainly notes hypoglycaemia (low blood sugar), water retention and, with prolonged or high use, the risk of unwanted growth of tissues and organs. That's exactly why it belongs in a controlled research setup and not in personal use.

Is IGF-1 LR3 legal?

In the Netherlands you may buy and sell IGF-1 LR3 for experimental laboratory research that isn't applied to humans or animals. It's not a medicine and isn't approved for human use anywhere. For athletes it's also important that IGF-1 and its analogues are explicitly on the WADA prohibited list (category S2, growth factors) and so banned in competition. At GradePurity you buy it strictly as a research-grade compound.

Purity & lab testing

IGF-1 LR3 is a complex 83-amino-acid protein, and that's exactly why purity matters all the more here: an impure batch behaves very differently in your research. We test every batch by HPLC for high purity (≥98%) and for identity, and ship it freeze-dried so it reaches you stable. The exact specifications are in the table at the bottom of this page.

Frequently asked questions

What our customers say.

Verified buyers across the Netherlands

★★★★★4.9 / 5Verified
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

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