Research onlyFor laboratory research · Not intended for human or animal application
GradePurity

HMG

Human menopausal gonadotropin, FSH + LH, 75 IU.

4.3 · 14 reviews
98% HPLCLab-verifiedResearch only
HMG, research-grade peptide vial
€ 59,95

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Bacteriostatic water

Needed to reconstitute lyophilised vials.

Insulin needles

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1
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Ships from NL · 1–2 day EU delivery
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HMG (human menopausal gonadotropin, also called menotropin) is a purified mixture of two gonadotropic hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH), in a roughly 1:1 ratio. Traditionally it is isolated from the urine of postmenopausal women. Unlike most products in our range, HMG is not a small peptide but a combination of glycoprotein hormones. In research it is studied around the hypothalamic-pituitary-gonadal axis, the chain that drives the gonads in both women and men. As a medicine, menotropin is known under brand names such as Menopur, Menogon and Pergonal and is used on prescription in fertility treatment. At GradePurity you buy HMG as a research-grade substance: a lyophilised 75 IU vial, shipped same-day from the Netherlands.

What does HMG do?

HMG delivers two hormones at once: FSH and LH. Together they form the signal that drives the gonads into activity, in women the ovaries (maturation of follicles), in men the testes (production of testosterone and the start of spermatogenesis). Where most substances in our range touch a single target, HMG covers the whole gonadotropic side: it brings both the FSH and the LH action. That is exactly why it plays such a central role in fertility research.

HMG vs. hCG

HMG and hCG are constantly compared because both act on the sex-hormone axis, but they do not bring the same thing. hCG mimics only LH: it acts directly on the gonads and stimulates testosterone production there. HMG, by contrast, delivers FSH and LH. That extra FSH is the difference that draws attention in research: FSH is the link that drives sperm maturation in men and follicle growth in women. In the literature the two are therefore often studied alongside or after one another, hCG for the LH side, HMG to add the FSH action as well. GradePurity does not sell hCG; this comparison is here purely for information.

HMG for men and after a cycle

Around male fertility and the recovery of the body’s own hormone axis, HMG is a much-discussed topic. The background: during an external androgen cycle the body’s own LH/FSH production stalls, which makes the testes less active and lowers both testosterone and sperm production. Because HMG brings both LH and FSH action, research looks at whether it can supplement the gonadotropic signals that are then missing, often in combination with hCG. What is known about this is described in the scientific literature.

Brands: Menopur, Menogon and Pergonal

As a medicine, menotropin has been in use for decades under various brand names. Menopur and Menogon (from Ferring) are the best-known highly purified versions, used on prescription in IVF and IUI treatment; Pergonal was one of the first HMG preparations and has largely been replaced by the newer, cleaner versions. Those branded products are prescription pharmaceutical injections, meant for supervised medical treatment. What GradePurity supplies is something different: HMG as a research-grade substance for laboratory use, not a medicine and not a replacement for one. We name the brands here only for recognition and to set them apart.

Dosage of HMG

In the medical literature HMG is dosed in international units (IU), with 75 IU a common base unit, hence the format of our vial. The exact amounts and schedules from clinical use belong to supervised treatment and say nothing about laboratory use. GradePurity therefore deliberately gives no dosing or administration advice and publishes no cycle schedules. The 75 IU designation and the other specifications are in the table at the bottom of this page, intended for your research documentation.

Side effects of HMG

In the clinical literature the side effects of menotropin are described mainly in the context of fertility treatment. Reported are, among others, injection-site reactions, headache, abdominal pain and, with stimulation of the ovaries, the risk of ovarian hyperstimulation syndrome (OHSS). These are observations from supervised medical use, not data about laboratory use. GradePurity supplies HMG solely as a research substance and gives no safety or dosing advice for personal use. For the full side-effect profile we refer to the medical literature and a doctor or pharmacist.

Purity and lab testing

HMG is a biological product: a mixture of glycoprotein hormones, not a synthetic peptide. That is precisely why testing matters. Every batch is checked in the lab for identity and for FSH/LH activity, so you know the vial contains what the label says. Per lot we record the data. That sets a controlled research-grade vial apart from an anonymous supplier. The specifications, origin, activity and storage conditions, are in the table at the bottom of this page.

Frequently asked questions

What our customers say.

Verified buyers across the Netherlands

★★★★★4.9 / 5Verified
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

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BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

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TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

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★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

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BPC-157
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Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

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Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

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★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

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★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

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Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

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Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

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TB-500
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

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