Research onlyFor laboratory research · Not intended for human or animal application
GradePurity

Semaglutide

GLP-1 analogue (31 amino acids), the research-grade vial, not the prescription medicine.

4.9 · 124 reviews
99.4% HPLCLab-verifiedBestsellerResearch only
Semaglutide, research-grade peptide vial
€ 54,95

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Bacteriostatic water

Needed to reconstitute lyophilised vials.

Insulin needles

Alcohol swabs

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1
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Ships from NL · 1–2 day EU delivery
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Semaglutide is a GLP-1 receptor agonist: a peptide of 31 amino acids that mimics the natural gut hormone GLP-1. In medicine it is known under the brand names Ozempic, Wegovy and Rybelsus (Novo Nordisk), where it is prescribed for type 2 diabetes and obesity. At GradePurity you buy semaglutide not as a medicine but as a research-grade vial: freeze-dried, ≥99% HPLC purity and same-day shipping from the Netherlands.

What does semaglutide do?

Semaglutide is a GLP-1 receptor agonist. In medicine it is used to lower blood sugar and curb appetite, which is why it is well known around type 2 diabetes and weight loss. In research it is one of the most studied incretin mimetics: substances that mimic the gut hormone GLP-1. Important to know: what GradePurity supplies is the research-grade vial for the lab, not the medicine. We make no health or weight-loss claims ourselves; semaglutide is a research material here, not for use in humans.

How does semaglutide work?

GLP-1 is a hormone your gut releases as soon as food comes in. Semaglutide is designed to mimic that hormone and stay active in the body for longer. Through the GLP-1 receptors it influences several processes at once in research: it stimulates insulin release when blood sugar rises, slows gastric emptying and acts on satiety centres in the brain. That combination explains the strong attention in medicine.

Semaglutide as a research-grade vial, not Ozempic or Wegovy

This is the most important distinction on this page. The semaglutide we sell is a research-grade vial: the pure, freeze-dried peptide for laboratory research. That is different from the registered medicines Ozempic, Wegovy and Rybelsus, which go through a prescription and a pharmacy, with their own dosing, guidance and monitoring. Our vial is not a replacement for that medical route and is explicitly not for human use. Researchers choose the vial because they want to work from the pure starting material and set the concentration themselves.

Semaglutide and the GLP-1 family

Semaglutide is part of a fast-growing family of research compounds around GLP-1. Tirzepatide adds a second route to the GLP-1 action (GIP), and retatrutide goes a step further with a third route. They are often compared in research because they act on related but slightly different parts of the metabolism. If you want to look at those other research compounds, you will find tirzepatide and retatrutide separately in our metabolic line. GradePurity supplies them all as a research material only.

Reconstituting the vial

Semaglutide ships as a freeze-dried powder in a sterile vial. In research it is mixed with bacteriostatic water and then dissolved for use in the lab. We deliberately give no human dosing advice: the right amount and approach depend on the study design, not on a usage dose. The details on this page (purity, vial size, sequence) are intended for your research documentation.

Side effects and safety

Because semaglutide is a potent substance, honesty matters here. In medicine, under supervision, side effects such as nausea, gastrointestinal complaints and reduced appetite are reported. Outside medical supervision there are actually more reports of poisoning with these GLP-1 substances, exactly the reason we supply it as a research material only and not for consumption.

Purity and lab testing

With a complex peptide like semaglutide, purity determines whether research is usable. That is why we test every batch by HPLC for ≥99% purity and identity, and ship it freeze-dried so it arrives stable. So you know exactly what you are holding, the exact specifications (purity, sequence, molecular weight, CAS) are in the table at the bottom of this page.

Frequently asked questions

What our customers say.

Verified buyers across the Netherlands

★★★★★4.9 / 5Verified
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

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