Research onlyFor laboratory research · Not intended for human or animal application
GradePurity

Survodutide

Dual agonist, GLP-1 · glucagon.

4.7 · 18 reviews
99.2% HPLCLab-verifiedPremiumResearch only
Survodutide, research-grade peptide vial
€ 79,95

Choose vial size

Bacteriostatic water

Needed to reconstitute lyophilised vials.

Insulin needles

Alcohol swabs

Quantity

1
Bulk discountup to −26%

1 more for −10% off

Free shipping from €125

In stock
Ships from NL · 1–2 day EU delivery
30-day returns
Secure payment
Survodutide (BI 456906) is a synthetic research peptide that acts as a dual agonist on two receptors at once: the GLP-1 receptor and the glucagon receptor. It is being developed by Boehringer Ingelheim and Zealand Pharma and is studied in Phase 3 trials around obesity and the liver disease MASH. That places it in the new generation of metabolic research peptides, alongside retatrutide. Survodutide is an investigational substance, not approved as a medicine anywhere. At GradePurity you buy it as a research-grade peptide: ≥99% HPLC purity and same-day shipping from the Netherlands.

What is survodutide?

Survodutide (also known by the code BI 456906) is a research peptide from the group of dual incretin agonists. "Dual" means it acts on two receptors at once: the GLP-1 receptor and the glucagon receptor. It is being developed by Boehringer Ingelheim and Zealand Pharma and is mainly in view in research around obesity and fatty liver disease (MASH). Unlike most known substances in this class, survodutide is not yet approved: it is in Phase 3 trials.

How does survodutide work?

Survodutide combines two routes of action in one molecule. Via the GLP-1 receptor it is, like semaglutide, linked to suppressing appetite and slowing gastric emptying. Via the glucagon receptor it is thought to additionally increase energy expenditure and act on fat metabolism in the liver. It is precisely this glucagon component that sets survodutide apart from pure GLP-1 substances, and which draws attention in research around fatty liver. Most of what we know comes from clinical studies.

Survodutide vs. retatrutide

Survodutide and retatrutide are often mentioned side by side, because both belong to the new generation of metabolic research peptides. The difference is in the number of receptors: survodutide is a dual agonist (GLP-1 + glucagon), while retatrutide is a triple agonist (GLP-1 + glucagon + GIP). In research, survodutide stands out mainly for its focus on fatty liver (MASH); retatrutide for the strong weight effects in early studies. If you want to compare both in research, you will find retatrutide separately in our range. GradePurity supplies single vials, no pre-mixed combinations.

Survodutide vs. semaglutide and tirzepatide (Ozempic/Mounjaro)

Survodutide is sometimes called "the little brother of Ozempic" online, but it works differently. Semaglutide (Ozempic, Wegovy) is a pure GLP-1 agonist; tirzepatide (Mounjaro) acts on GLP-1 and GIP. Survodutide combines GLP-1 with glucagon, a route neither of them uses. That glucagon component is why survodutide is looked at separately in research, particularly for the liver. Important: semaglutide and tirzepatide are approved medicines, survodutide is not. GradePurity supplies survodutide solely as a research substance.

Research status: Phase 3, obesity and MASH

Survodutide is in Phase 3 trials, the final stage before any approval is sought. The research runs in two Phase 3 programmes: SYNCHRONIZE in obesity and LIVERAGE in MASH (metabolic dysfunction-associated steatohepatitis), a form of fatty liver. For MASH, the substance received a Breakthrough Therapy designation from the US FDA in 2024. At present, however, survodutide is not approved as a medicine anywhere. What is described in the studies and the medical literature can be found there.

Reconstituting and storing survodutide

Survodutide is supplied as a lyophilised powder in a vial. For research it is mixed with bacteriostatic water; GradePurity gives no dosing or administration advice, because we supply it solely as a research peptide. Store the unopened vial dry, dark and cool. After mixing, the solution goes in the fridge (2–8 °C), protected from light; for longer storage the vial can go in the freezer. The details on this page are intended for research documentation.

Purity and lab testing

Every batch of survodutide is checked in the lab for purity (≥99% HPLC) and identity. So you know exactly what you are holding, that is the main difference from anonymous suppliers. A certificate of analysis (COA) is available per lot. The exact specifications are in the table at the bottom of this page.

Frequently asked questions

What our customers say.

Verified buyers across the Netherlands

★★★★★4.9 / 5Verified
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
View all peptides
Often ordered together

Others also bought.

View all peptides