Research onlyFor laboratory research · Not intended for human or animal application
GradePurity

Tirzepatide

Dual agonist, GLP-1 · GIP.

4.9 · 87 reviews
99.4% HPLCLab-verifiedBestsellerResearch only
Tirzepatide, research-grade peptide vial
€ 54,95

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Bacteriostatic water

Needed to reconstitute lyophilised vials.

Insulin needles

Alcohol swabs

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1
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Ships from NL · 1–2 day EU delivery
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Tirzepatide (Eli Lilly code LY-3298176) is a synthetic research peptide that acts as a dual agonist on two receptors at once: the GLP-1 receptor and the GIP receptor. It is the substance that became clinically known under the brand names Mounjaro and Zepbound, where it is used by prescription. At GradePurity you buy tirzepatide not as a medicine, but as a research-grade peptide: a lyophilised vial with ≥99% HPLC purity, shipped same-day from the Netherlands. It belongs to the metabolic research peptides, alongside semaglutide (single) and retatrutide (triple).

What does tirzepatide do?

Tirzepatide is a research peptide from the group of incretin agonists. What makes it distinctive is that it acts on two receptors at once: the GLP-1 receptor and the GIP receptor. That makes it a "dual agonist". In the scientific literature, tirzepatide is best known for its role in research around glucose handling and weight regulation; clinically, most people know it under the name Mounjaro.

How does tirzepatide work?

Tirzepatide combines two routes of action in one molecule. Via the GLP-1 receptor it is, like semaglutide, linked to suppressing appetite and slowing gastric emptying. In addition, it acts on the GIP receptor, a second incretin route that pure GLP-1 substances do not use. It is thought that precisely this combination of GLP-1 and GIP leads to a stronger metabolic response in research than a GLP-1 substance alone. What we know about this comes almost entirely from clinical studies.

Tirzepatide vs. semaglutide (Ozempic) and retatrutide

The three best-known metabolic peptides differ mainly in the number of receptors they act on. Semaglutide (Ozempic, Wegovy) is a single GLP-1 agonist: one switch. Tirzepatide adds GIP and is therefore dual: two switches. Retatrutide goes one step further and also activates the glucagon receptor, a triple agonist with three switches. In terms of mechanism, tirzepatide sits exactly between semaglutide and retatrutide. Important difference: semaglutide and tirzepatide are approved medicines, retatrutide is not (yet). If you want to compare them in research, you will find semaglutide and retatrutide separately in our range.

Tirzepatide, Mounjaro and Zepbound

Tirzepatide is the active substance behind the brand names Mounjaro and Zepbound from manufacturer Eli Lilly. Under those names it is dispensed by prescription through the pharmacy, as a pre-filled pen. What GradePurity supplies is something different: not a branded medicine and not a pen, but tirzepatide as a single, lyophilised research-grade vial for laboratory research. The substance is the same dual GLP-1/GIP agonist, but the context is entirely different, a research vial is not intended for human use and does not replace a prescription or medical supervision. If you are looking for the prescription medicine, a pharmacy is the right place; if you are looking for the research substance, we supply it.

Side effects of tirzepatide

In clinical research, the most commonly described side effects of tirzepatide are gastrointestinal: nausea, diarrhoea, reduced appetite and constipation, mainly in the first weeks and when increasing the dose. These are observations from studies in humans under medical supervision, not data that says anything about laboratory use. GradePurity supplies tirzepatide solely as a research substance and gives no dosing or safety advice for personal use. For the full side effects and contraindications of the medicine, we refer to the official package leaflet and your doctor or pharmacist.

Reconstituting and storing tirzepatide

Tirzepatide is supplied as a lyophilised powder in a vial. For research it is mixed with bacteriostatic water; GradePurity gives no dosing or administration advice, because we supply it solely as a research peptide. Store the unopened vial dry, dark and cool. After mixing, the solution goes in the fridge (2–8 °C), protected from light; for longer storage the vial can go in the freezer. The specifications in the table at the bottom of this page are intended for your research documentation.

Purity and lab testing

Every batch of tirzepatide is checked in the lab for purity (≥99% HPLC) and identity. So you know exactly what you are holding, and that is the real difference from anonymous suppliers. Per lot we record the purity and identity data. The exact specifications, sequence, molecular weight and purity, are in the table at the bottom of this page.

Frequently asked questions

What our customers say.

Verified buyers across the Netherlands

★★★★★4.9 / 5Verified
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

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