Research onlyFor laboratory research · Not intended for human or animal application
GradePurity

Retatrutide

Triple agonist, GLP-1 · GIP · Glucagon.

4.8 · 34 reviews
99.3% HPLCLab-verifiedHot SKUResearch only
Retatrutide, research-grade peptide vial
€ 69,95

Choose vial size

Bacteriostatic water

Needed to reconstitute lyophilised vials.

Insulin needles

Alcohol swabs

Quantity

1
Bulk discountup to −26%

1 more for −10% off

Free shipping from €125

In stock
Ships from NL · 1–2 day EU delivery
30-day returns
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Retatrutide (LY3437943) is a synthetic triple-agonist peptide that acts on the GLP-1, GIP and glucagon receptors at once, one of the most advanced metabolic triagonists from the Phase 3 research of Eli Lilly. While still in the research stage as a medicine, you can now buy retatrutide from GradePurity as a research-grade peptide: ≥99% HPLC purity and same-day shipping from the Netherlands. Available as a vial or a ready-to-use pen.

What does retatrutide do?

Retatrutide is the metabolic research peptide everyone is talking about right now, mostly because of the striking weight-loss results in Eli Lilly's large Phase 3 research. It is a so-called triple agonist: it works on three "switches" in the body at once, GLP-1, GIP and glucagon, which control hunger, blood sugar and energy expenditure. It is thought that this very threefold action takes retatrutide a step beyond older options such as semaglutide (Ozempic) and tirzepatide.

How does retatrutide work?

Put simply, retatrutide works on three pathways at once. The GLP-1 and GIP pathways curb appetite and help keep blood sugar balanced; the glucagon pathway gives energy expenditure an extra push on top. No other known weight-loss peptide has that third pathway, and it is thought the combination therefore goes further than single GLP-1 options. The full action is being studied in Eli Lilly's Phase 3 TRIUMPH programme; as a medicine retatrutide is not yet approved.

Retatrutide vs. Ozempic

The difference in one sentence: Ozempic (semaglutide) presses one switch, retatrutide presses three. Ozempic is a single GLP-1 agonist; retatrutide also activates GIP and glucagon. Tirzepatide (Mounjaro) sits in between with two pathways. So retatrutide is not the same as Ozempic, but its own, newer research peptide, studied precisely for that extra mechanism.

Side effects of retatrutide

In the Phase 3 research, the most commonly reported reactions were gastrointestinal, nausea, reduced appetite, sometimes diarrhoea, usually mild and mostly early on, much like other GLP-1 options.

Purity and lab testing

Every batch of retatrutide is checked in the lab for purity (≥99%) and identity. So you know exactly what you are holding, that is the main difference from anonymous suppliers. The exact specifications are in the table at the bottom of this page.

Retatrutide as a vial or pen

You can choose retatrutide as a lyophilised vial or a ready-to-use pen. You mix the vial yourself with bacteriostatic water; the pen is pre-filled and ready to go. Both have the same ≥99% purity, it is purely a matter of convenience.

Reconstitution and storage

Mix the vial with bacteriostatic water according to protocol and then store it in the fridge (2–8 °C); use it within about 28 days. To convert vial size, water and target dose into a week-by-week schedule, use the retatrutide titration tool.

For laboratory research only

All GradePurity products, retatrutide included, are intended for in-vitro and laboratory research. They are not intended for human or animal consumption, diagnostics or treatment.

Retatrutide from China?

Our retatrutide comes, like nearly all research peptides, from China, but already imported, tested with a COA per batch and in EU stock. No 3-4 week wait, no customs risk.

More about peptides from China

Frequently asked questions

What our customers say.

Verified buyers across the Netherlands

★★★★★4.9 / 5Verified
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Well and discreetly packed, will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. Unbranded envelope, my courier had no idea what was inside.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Payment went flawlessly.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so no customs hassle. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Arrived in a plain, neutral envelope. My neighbour who took it in literally had no clue what was inside. Privacy = 10.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Payment trouble-free. Identity neatly confirmed by MS on the COA.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Completely neutral packaging, nothing visible on the outside. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

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